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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LASMIDITAN
| LASMIDITAN | NERVOUS SYSTEM | ORAL | Tmax 1.8 HOUR PPB 57.5 PERCENT HT 5.7 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | SEROTONIN (5-HT) 1F RECEPTOR PDB 7EXD (LASMIDITAN-BOUND SEROTONIN 1F (5-HT1F) RECEPTOR-GI PROTEIN COMPLEX) LIGAND CODE = 05X (link to the list of PDB complexes) Download experimental 3D coordinates of 05X with added hydrogens | 5-hydroxytryptamine receptor 1F UNIPROT P30939 HTR1F more at DrugCentral | EMA | |||
