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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
AFAMELANOTIDE

AFAMELANOTIDE


ATC D02BB02

DERMATOLOGICALS
MELANOCORTIN 1 RECEPTOR (MC1-R) AGONIST
TREATMENT OF PHOTOTOXIC REACTIONS FROM ERYTHROPOIETIC PROTOPORPHYRIA (EPP)
A STRUCTURAL ANALOG OF ALPHA-MELANOCYTE STIMULATING HORMONE (ALPHA-MSH)

SUBCUTANEOUS

Cmax 2.2 NANOMOLAR

Tmax 36 HOUR

HT 15 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

MELANOCORTIN 1 RECEPTOR (MC1-R)

Melanocyte-stimulating hormone receptor agonist Q01726 MSHR_HUMANANSM (in French)

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