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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BREMELANOTIDE

BREMELANOTIDE


ATC G02CX05

MELANOCORTIN RECEPTOR (MCR) AGONIST
TREATMENT OF PREMENOPAUSAL WOMEN WITH ACQUIRED, GENERALIZED HYPOACTIVE SEXUAL DESIRE DISORDER (HSDD)

SUBCUTANEOUS

Cmax 71 NANOMOLAR

Tmax 1 HOUR

F 100 PERCENT

VD 25 LITER

PPB 21 PERCENT

Cl 6.5 LITER / HOUR

HT 2.7 HOUR

MELANOCORTIN RECEPTOR (MCR) MC1R, MC4R, MC3R, MC5R, MC2R

Melanocortin receptor 4 agonist P32245 MC4R_HUMANANSM (in French)

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