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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMISULPRIDE
| AMISULPRIDE | NERVOUS SYSTEM | INTRAVENOUS | Cmax 541.6 NANOMOLAR (5 MG) VD 171 LITER PPB 27.5 PERCENT Cl 24.1 LITER / HOUR HT 4.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | DOPAMINE-2 (D2) RECEPTOR DOPAMINE-3 (D3) RECEPTOR | D(2) dopamine receptor UNIPROT P14416 DRD2 -- D(3) dopamine receptor UNIPROT P35462 DRD3 more at DrugCentral | EMA | |||
