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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LUSUTROMBOPAG

LUSUTROMBOPAG


ATC B02BX07

BLOOD
THROMBOPOIETIN RECEPTOR (TPO) AGONIST
TREATMENT OF THROMBOCYTOPENIA

ORAL

Cmax 187.7 NANOMOLAR

Tmax 7 HOUR

VD 39.5 LITER

PPB 99.9 PERCENT

Cl 1.1 LITER / HOUR

HT 27 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

THROMBOPOIETIN RECEPTOR

Thrombopoietin receptor UNIPROT P40238 MPL

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