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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MOXIDECTIN

MOXIDECTIN


ATC P02CX03

ANTIPARASITIC
ANTHELMINTIC
TREATMENT OF ONCHOCERCIASIS
MACROCYCLIC LACTONE
MILBEMYCIN

ORAL

Cmax 92.1 NANOMOLAR

Tmax 4 HOUR

VD 2421 LITER

Cl 3.5 LITER / HOUR

HT 784 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER (0.51 MILLIGRAM PER LITER)

GLUTAMATE-GATED CHLORIDE CHANNELS (GLUCL)

Glutamate-gated chloride channel UNIPROT Q25634 GluClX

more at DrugCentral

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