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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GLASDEGIB
| GLASDEGIB | ANTINEOPLASTIC | ORAL | Cmax 3.3 MICROMOLAR Tmax 1.55 HOUR F 77 PERCENT VD 188 LITER PPB 91 PERCENT Cl 6.45 LITER / HOUR HT 17.4 HOUR SOLUBILITY SOLUBLE IN WATER (1.7 MILLIGRAM PER MILLIMITER) | SMOOTHENED (SMO) | Smoothened homolog UNIPROT Q99835 SMO more at DrugCentral | EMA | |||
