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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M REVEFENACIN (is an active metabolite)

REVEFENACIN


ATC R03BB08

RESPIRATORY
TREATMENT OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)
ANTICHOLINERGIC
MUSCARINIC ANTAGONIST LEADING TO BRONCHODILATION

-

Cmax 0.33 NANOMOLAR

Tmax 0.45 HOUR

PPB 42 PERCENT

HT 46 HOUR

MUSCARINIC RECEPTORS M1 TO M5

Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1 -- Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2

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