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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| REVEFENACIN (has an active metabolite)
| REVEFENACIN | RESPIRATORY | INHALATION | Cmax 0.26 NANOMOLAR Tmax 0.45 HOUR F 3 PERCENT (INHALATION COMPARED TO ORAL) VD 218 LITER PPB 71 PERCENT HT 46 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | MUSCARINIC RECEPTORS M1 TO M5 | Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1 -- Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 more at DrugCentral | EMA | |||
