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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TAFENOQUINE
| TAFENOQUINE | ANTIPARASITIC | ORAL | Cmax 317 NANOMOLAR Tmax 14 HOUR VD 2470 LITER PPB 99.5 PERCENT Cl 4.2 LITER / HOUR HT 396 HOUR | PDB 7DDC (CRYSTAL STRUCTURE OF SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH TAFENOQUINE) LIGAND CODE = H3F (link to the list of PDB complexes) Download experimental 3D coordinates of H3F with added hydrogens | Unknown more at DrugCentral | EMA | |||
