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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ENCORAFENIB
| ENCORAFENIB | ANTINEOPLASTIC | ORAL | Tmax 2 HOUR F 86 PERCENT VD 164 LITER PPB 86 PERCENT Cl 14 LITER / HOUR HT 3.5 HOUR SOLUBILITY INSOLUBLE IN WATER AT PH 3 AND HIGHER | BRAF | RAF proto-oncogene serine,threonine-protein kinase UNIPROT P04049 RAF1 -- Serine,threonine-protein kinase B-raf UNIPROT P15056 BRAF more at DrugCentral | EMA | |||
