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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ELAGOLIX
| ELAGOLIX | HORMONES | ORAL | Cmax 1.22 MICROMOLAR Tmax 1 HOUR VD 881 LITER PPB 80 PERCENT Cl 144 LITER / HOUR HT 5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | GONADOTROPIN-RELEASING HORMONE RECEPTOR PDB 7BR3 (CRYSTAL STRUCTURE OF THE PROTEIN 1) LIGAND CODE = F5O (link to the list of PDB complexes) Download experimental 3D coordinates of F5O with added hydrogens | Gonadotropin-releasing hormone receptor UNIPROT P30968 GNRHR more at DrugCentral | EMA | |||
