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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ERTUGLIFLOZIN

ERTUGLIFLOZIN


ATC A10BK04
ATC A10BD23
ATC A10BD24

METABOLISM
TYPE 2 DIABETES MELLITUS
SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2) INHIBITOR

ORAL

Cmax 613.7 NANOMOLAR (15 MILLIGRAM)

Tmax 1 HOUR

VD 85.5 LITER

PPB 93.6 PERCENT

Cl 11.2 LITER / HOUR

HT 16.6 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

SODIUM-GLUCOSE CO-TRANSPORTER 2 (SGLT2)

Sodium,glucose cotransporter 2 UNIPROT P31639 SLC5A2

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