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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BENZNIDAZOLE

BENZNIDAZOLE


ATC P01CA02

ANTIPARASITIC
A NITROIMIDAZOLE ANTIMICROBIAL
TREATMENT OF CHAGAS DISEASE CAUSED BY TRYPANOSOMA CRUZI
BENZNIDAZOLE INHIBITS THE SYNTHESIS OF DNA, RNA, AND PROTEINS WITHIN THE T. CRUZI PARASITE

ORAL

Cmax 9.2 NANOMOLAR

Tmax 2 HOUR

PPB 52 PERCENT

HT 13 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

DNA

Unknown

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