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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MMAE
| MMAE BRENTUXIMAB VEDOTIN POLATUZUMAB VEDOTIN-PIIQ ENFORTUMAB VEDOTIN-EJFV | ANTINEOPLASTIC | INJECTION INTRAVENOUS | PPB 75 PERCENT | TUBULIN PDB 5IYZ (TUBULIN-MMAE COMPLEX) LIGAND CODE = 4Q5 (link to the list of PDB complexes) Download experimental 3D coordinates of 4Q5 with added hydrogens | TUBULIN TBB1_HUMAN INHIBITOR UNIPROT P04350 more at DrugCentral | EMA | |||
