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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVOLEUCOVORIN (has an active metabolite)
| LEVOLEUCOVORIN LEUCOVORIN |
VARIOUS | INJECTION ORAL INTRAVENOUS | VD 16.2 LITER (65 KILOGRAM) PPB 91 PERCENT Cl 22.6 LITER / HOUR (65 KILOGRAM) HT 1.3 HOUR SOLUBILITY SOLUBLE IN WATER | PDB 3UWL (CRYSTAL STRUCTURE OF ENTEROCCOCUS FAECALIS THYMIDYLATE SYNTHASE (EFTS) IN COMPLEX WITH 5-FORMYL TETRAHYDROFOLATE) LIGAND CODE = FOZ (link to the list of PDB complexes) Download experimental 3D coordinates of FOZ with added hydrogens | Unknown more at DrugCentral | EMA | |||
