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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
VELPATASVIR

VELPATASVIR


ATC J05AP55
ATC J05AP56

ANTIINFECTIVES
HEPATITIS C VIRUS (HCV) NS5A INHIBITOR

ORAL

Cmax 293 NANOMOLAR

Tmax 3 HOUR

PPB 99.5 PERCENT

HT 15 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER ABOVE PH 5

NS5A

Genome polyprotein UNIPROT P26663 -- Genome polyprotein UNIPROT P27958

more at DrugCentral

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ANSM (in French)

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ChEMBL
BindingDB
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