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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TIPIRACIL
| TIPIRACIL | ANTINEOPLASTIC | ORAL | PPB 8 PERCENT HT 2.1 HOUR SOLUBILITY SOLUBLE IN WATER | THYMIDINE PHOSPHORYLASE PDB 1UOU (CRYSTAL STRUCTURE OF HUMAN THYMIDINE PHOSPHORYLASE IN COMPLEX WITH A SMALL MOLECULE INHIBITOR) LIGAND CODE = CMU (link to the list of PDB complexes) Download experimental 3D coordinates of CMU with added hydrogens | Thymidine phosphorylase UNIPROT P19971 TYMP more at DrugCentral | EMA | |||
