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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DESOXYCORTICOSTERONE (is an active metabolite)

DESOXYCORTICOSTERONE


ATC H02AA03

HORMONES
ADRENOCORTICAL STEROID
PRECURSOR OF ALDOSTERONE
SUBSTRATE OF ALDOSTERONE SYNTHASE (CYTOCHROME P450 CYP11B2)

- ALDOSTERONE SYNTHASE

PDB 2AA7 (MINERALOCORTICOID RECEPTOR WITH BOUND DEOXYCORTICOSTERONE)

LIGAND CODE = 1CA (link to the list of PDB complexes)

Download experimental 3D coordinates of 1CA with added hydrogens

Mineralocorticoid receptor UNIPROT P08235 NR3C2

more at DrugCentral

EMA

ANSM (in French)

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SIDER side effects

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ChEMBL
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