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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ELUXADOLINE
| ELUXADOLINE | NERVOUS SYSTEM | ORAL | Cmax 5.27 NANOMOLAR Tmax 1.5 HOUR PPB 81 PERCENT HT 4.8 HOUR | MU-OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 -- Delta-type opioid receptor UNIPROT P41143 OPRD1 more at DrugCentral | EMA | |||
