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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DACLATASVIR DISCONTINUED

DACLATASVIR


ATC J05AP07
ATC J05AP58

ANTIINFECTIVES
INHIBITOR OF HCV NONSTRUCTURAL PROTEIN 5A (NS5A)

ORAL

Tmax 2 HOUR

F 67 PERCENT

VD 47 LITER

PPB 99 PERCENT

Cl 4.2 LITER / HOUR

HT 13.5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

NS5A

Genome polyprotein UNIPROT P26663 -- Genome polyprotein UNIPROT P27958

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