| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| THIOPENTAL DISCONTINUED
| THIOPENTAL | NERVOUS SYSTEM | RECTAL | VD 78 LITER (65 KILOGRAM) PPB 80 PERCENT Cl 32 LITER / HOUR (65 KILOGRAM) HT 5.5 HOUR | GAMMA-AMINOBUTYRIC-ACID RECEPTOR | GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1 more at DrugCentral | EMA | |||
