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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OLODATEROL
| OLODATEROL | RESPIRATORY SYSTEM | INHALATION | Tmax 0.25 HOUR F 30 PERCENT VD 1110 LITER PPB 60 PERCENT Cl 52.3 LITER / HOUR HT 45 HOUR SOLUBILITY SPARINGLY-SLIGHTLY SOLUBLE IN WATER | BETA2 ADRENERGIC RECEPTOR PDB 8JJL (CRYO-EM STRUCTURE OF THE BETA2-AR-MBRIL, 1B3 FAB, GLUE COMPLEX WITH A FULL AGONIST) LIGAND CODE = DZQ (link to the list of PDB complexes) Download experimental 3D coordinates of DZQ with added hydrogens | Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
