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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PARITAPREVIR
| PARITAPREVIR | ANTIINFECTIVES | ORAL | Cmax 342.4 NANOMOLAR Tmax 4.5 HOUR VD 16.7 LITER PPB 97.8 PERCENT Cl 2.1 LITER / HOUR (EQN) HT 5.5 HOUR SOLUBILITY VERY LOW WATER SOLUBILITY | HCV NS3/4A PROTEASE | Unknown more at DrugCentral | EMA | |||
