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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEDIPASVIR
| LEDIPASVIR | ANTIINFECTIVES | ORAL | Cmax 363.7 NANOMOLAR Tmax 4.25 HOUR PPB 99.8 PERCENT HT 47 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | HCV NS5A | Genome polyprotein UNIPROT P26663 -- Genome polyprotein UNIPROT P27958 more at DrugCentral | EMA | |||
