| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PERINDOPRILAT (is an active metabolite)
| PERINDOPRILAT |
CARDIOVASCULAR | - | Tmax 5 HOUR F 25 PERCENT VD 49.4 LITER (65 KILOGRAM) PPB 15 PERCENT Cl 6.6 LITER / HOUR (65 KILOGRAM) HT 29 HOUR | ANGIOTENSIN-CONVERTING ENZYME PDB 2X94 (CRYSTAL STRUCTURE OF ANCE-PERINDOPRILAT COMPLEX) LIGAND CODE = X94 (link to the list of PDB complexes) Download experimental 3D coordinates of X94 with added hydrogens | Angiotensin-converting enzyme UNIPROT P12821 ACE more at DrugCentral | EMA | |||
