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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M LOSARTAN (is an active metabolite)

LOSARTAN


ATC C09CA01
ATC C09DB06
ATC C09DA01

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN II RECEPTOR ANTAGONIST
ANTI-ARRHYTHMIA AGENTS

-

Tmax 3.5 HOUR

VD 12 LITER

PPB 99.8 PERCENT

Cl 3 LITER / HOUR

HT 7.5 HOUR

TYPE-1 ANGIOTENSIN II RECEPTOR

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

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