| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRANDOLAPRILAT (is an active metabolite)
| TRANDOLAPRILAT | CARDIOVASCULAR | - | Tmax 7 HOUR F 70 PERCENT VD 227 LITER (EQN) PPB 65 PERCENT Cl 7 LITER / HOUR HT 22.5 HOUR | ANGIOTENSIN-CONVERTING ENZYME PDB 2X93 (CRYSTAL STRUCTURE OF ANCE-TRANDOLAPRILAT COMPLEX) LIGAND CODE = X93 (link to the list of PDB complexes) Download experimental 3D coordinates of X93 with added hydrogens | Angiotensin-converting enzyme UNIPROT P12821 ACE more at DrugCentral | EMA | |||
