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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M TAZAROTENE (is an active metabolite)
| TAZAROTENE | DERMATOLOGIC AGENTS | - | Cmax 37.1 NANOMOLAR PPB 99 PERCENT HT 18 HOUR | RETINOIC ACID RECEPTOR GAMMA RETINOIC ACID RECEPTOR BETA RETINOIC ACID RECEPTOR ALPHA | Retinoic acid receptor alpha UNIPROT P10276 RARA -- Retinoic acid receptor beta UNIPROT P10826 RARB more at DrugCentral | EMA | |||
