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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PREDNISONE

PREDNISONE


ATC A07EA03
ATC H02AB07

METABOLISM
GLUCOCORTICOID
ANTI-INFLAMMATORY AGENTS
ANTINEOPLASTIC AGENTS
ADRENOCORTICAL STEROIDS

ORAL

Cmax 801 NANOMOLAR (PMID21982386)

Tmax 2.2 HOUR

VD 37 LITER (65 KILOGRAM)

PPB 73 PERCENT

Cl 11 LITER / HOUR

HT 2.6 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

GLUCOCORTICOID RECEPTOR

Glucocorticoid receptor UNIPROT P04150 NR3C1

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