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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M RIFAPENTINE (is an active metabolite)

RIFAPENTINE


ATC J04AB05

ANTIINFECTIVES
TUBERCULOSTATIC
ANTIBIOTIC
RIFAMYCIN ANTIMYCOBACTERIALS
INHIBITS DNA-DEPENDENT RNA POLYMERASE

-

Cmax 7.5 MICROMOLAR

Tmax 11.2 HOUR

PPB 93.2 PERCENT

HT 13 HOUR

DNA-DIRECTED RNA POLYMERASE

Bacterial DNA-directed RNA polymerase UNIPROT P0A7Z4 rpoA

more at DrugCentral

EMA

ANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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