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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHYPRYLON DISCONTINUED
| METHYPRYLON | NERVOUS SYSTEM | ORAL | VD 63 LITER (65 KILOGRAM) Cl 0.77 LITER / HOUR (65 KILOGRAM) HT 9.2 HOUR (PMID2866242) | GABA-A receptor alpha-1,beta-3,gamma-2 UNIPROT P14867 GABRA1 more at DrugCentral | EMA | ||||
