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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROXYCHLOROQUINE
| HYDROXYCHLOROQUINE | ANTIPARASITIC | ORAL | Cmax 1.2 MICROMOLAR (PMID19188392) Tmax 2.4 HOUR VD 2851 LITER PPB 43 PERCENT Cl 12 LITER / HOUR HT 172.3 HOUR SOLUBILITY SOLUBLE IN WATER | Toll-like receptor 7 UNIPROT Q9NYK1 TLR7 -- Toll-like receptor 9 UNIPROT Q9NR96 TLR9 more at DrugCentral | EMA | ||||
