| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ALOGLIPTIN
| ALOGLIPTIN |
METABOLISM | ORAL | F 100 PERCENT VD 417 LITER PPB 20 PERCENT Cl 14 LITER / HOUR HT 21 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | DIPEPTIDYL PEPTIDASE-4 (DPP-4) PDB 3G0B (CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH TAK-322) LIGAND CODE = T22 (link to the list of PDB complexes) Download experimental 3D coordinates of T22 with added hydrogens | Dipeptidyl peptidase 4 UNIPROT P27487 DPP4 more at DrugCentral | EMA | |||
