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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CARFILZOMIB
| CARFILZOMIB | ANTINEOPLATIC | INTRAVENOUS INJECTION | Cmax 5.8 MICROMOLAR VD 28 LITER PPB 97 PERCENT Cl 207 LITER / HOUR HT 1 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | 20S PROTEASOME | Proteasome subunit beta type-5 UNIPROT P28074 PSMB5 more at DrugCentral | EMA | |||
