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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LORCASERIN

LORCASERIN


ATC A08AA11

METABOLISM
SEROTONIN 2C RECEPTOR AGONIST 5-HT2C (KD = 13 NANOMOLAR)
5-HT2B (KD = 147 NANOMOLAR)
5-HT2A (KD = 92 NANOMOLAR)
WEIGHT MANAGEMENT IN ADULTS
ANOREXIGENIC

ORAL

Tmax 1.75 HOUR

PPB 70 PERCENT

HT 11 HOUR

SOLUBILITY SOLUBILITY IN WATER GREATER THAN 400 MILLIGRAM / MILLILITER

SEROTONIN 2C RECEPTOR (5-HT2C)

5-hydroxytryptamine receptor 2C UNIPROT P28335 HTR2C

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