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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LOMITAPIDE
| LOMITAPIDE | CARDIOVASCULAR | ORAL | F 7 PERCENT VD 1138 LITER PPB 99.8 PERCENT Cl 19.8 LITER / HOUR (EQN) HT 39.7 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN AQUEOUS SOLUTIONS OF PH 2 TO 5 | MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN | Microsomal triglyceride transfer protein large subunit UNIPROT P55157 MTTP more at DrugCentral | EMA | |||
