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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M OSELTAMIVIR (is an active metabolite)
| OSELTAMIVIR | ANTIINFECTIVES | - | Cmax 1.22 MICROMOLAR VD 24.5 LITER PPB 3 PERCENT Cl 2.1 LITER / HOUR (EQN) HT 8 HOUR | NEURAMINIDASE PDB 4QN7 (CRYSTAL STRUCTURE OF NEURAMNIDASE N7 COMPLEXED WITH OSELTAMIVIR) LIGAND CODE = G39 (link to the list of PDB complexes) Download experimental 3D coordinates of G39 with added hydrogens | Neuraminidase UNIPROT P03468 -- Neuraminidase UNIPROT P03474 more at DrugCentral | EMA | |||
