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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANDESARTAN (is an active metabolite)

CANDESARTAN


ATC C10BX19
ATC C09CA06
ATC C09DB07
ATC C09DA06
ATC C09DX06

CARDIOVASCULAR
ANTIHYPERTENSIVE
CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST
CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II

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F 15 PERCENT

VD 8.4 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 1.4 LITER / HOUR (65 KILOGRAM)

HT 9 HOUR

ANGIOTENSIN II RECEPTOR AT1

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

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