| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMFENAC (is an active metabolite)
| AMFENAC | SENSORY | - | Cmax 1.65 NANOMOLAR Tmax 0.75 HOUR PPB 99.1 PERCENT | PROSTAGLANDIN H SYNTHASE (CYCLOOXYGENASE) | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA | |||
