Cheminformatic Tools and Databases for Pharmacology

session 25383 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLEVIDIPINE

CLEVIDIPINE


ATC C08CA16

CARDIOVASCULAR
VASODILATOR
ANTIHYPERTENSIVE
DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKER
REDUCTION OF BLOOD PRESSURE
THE CARBOXYLIC ACID METABOLITE IS INACTIVE AS AN ANTIHYPERTENSIVE

INTRAVENOUS

VD 11 LITER (65 KILOGRAM)

PPB 99.5 PERCENT

Cl 30.5 LITER / HOUR (EQN)

HT 0.25 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

L-TYPE CALCIUM CHANNEL BLOCKER

Voltage-dependent L-type calcium channel subunit alpha-1C UNIPROT Q13936 CACNA1C -- Voltage-dependent L-type calcium channel subunit alpha-1D UNIPROT Q01668 CACNA1D

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |