| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M FIDAXOMICIN (is an active metabolite)
| FIDAXOMICIN | ANTIINFECTIVES | - | Cmax 12.1 NANOMOLAR (200 MILLIGRAM) Tmax 1.02 HOUR HT 11.2 HOUR | BETA SUBUNIT OF RNA POLYMERASE | DNA-directed RNA polymerase UNIPROT Q182S6 rpoZ more at DrugCentral | EMA | |||
