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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ICATIBANT

ICATIBANT


ATC B06AC02

BLOOD
PEPTIDE
INFLAMMATION
PAIN
HEREDITARY ANGIOEDEMA
BRADYKININ B2 RECEPTOR ANTAGONIST

SUBCUTANEOUS

Cmax 0.747 MICROMOLAR (30 MILLIGRAM)

F 97 PERCENT (30 MILLIGRAM)

VD 29 LITER

Cl 14.7 LITER / HOUR

HT 1.4 HOUR

BRADYKININ B2 RECEPTOR

B2 bradykinin receptor UNIPROT P30411 BDKRB2

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