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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEFERIPRONE

DEFERIPRONE


ATC V03AC02

VARIOUS
IRON CHELATOR
CHELATING AGENT
THALASSEMIA

ORAL

Cmax 143.8 MICROMOLAR (1500 MILLIGRAM)

VD 104 LITER (65 KILOGRAM)

PPB 10 PERCENT

Cl 37.9 LITER / HOUR (EQN)

HT 1.9 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN DEIONIZED WATER

FERRIC ION (IRON III)

Unknown

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