Cheminformatic Tools and Databases for Pharmacology

session 7293 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DIGOXIN

DIGOXIN


ATC C01AA05

CARDIOVASCULAR
ANTI-ARRHYTHMIA AGENTS
CARDIOTONIC AGENTS
DIGOXIN IS EXTRACTED FROM THE LEAVES OF DIGITALIS LANATA
SODIUM-POTASSIUM ATPASE INHIBITOR

INJECTION ORAL

Tmax 2 HOUR

F 70 PERCENT

VD 266 LITER (65 KILOGRAM)

PPB 25 PERCENT

Cl 6.6 LITER / HOUR (65 KILOGRAM)

HT 42 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

SODIUM-POTASSIUM ATPASE

PDB 4RET (CRYSTAL STRUCTURE OF THE NA,K-ATPASE E2P-DIGOXIN COMPLEX WITH BOUND MAGNESIUM)

LIGAND CODE = DGX (link to the list of PDB complexes)

Download experimental 3D coordinates of DGX with added hydrogens

Sodium,potassium-transporting ATPase UNIPROT P05023 ATP1A1

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |