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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ABIRATERONE ACETATE (has an active metabolite)
| ABIRATERONE ACETATE |
ANTINEOPLASTIC | ORAL | SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | 17 ALPHA-HYDROXYLASE/C17,20-LYASE (CYP17) | Steroid 17-alpha-hydroxylase,17,20 lyase UNIPROT P05093 CYP17A1 more at DrugCentral | EMA | |||
