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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BOCEPREVIR DISCONTINUED
| BOCEPREVIR | ANTIINFECTIVES | ORAL | Cmax 3.3 MICROMOLAR (800 MILLIGRAM) VD 772 LITER (800 MILLIGRAM) PPB 75 PERCENT Cl 161 LITER / HOUR HT 3.4 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | HCV NON-STRUCTURAL PROTEIN 3 (NS3) SERINE PROTEASE | Hepatitis C virus serine protease, NS3,NS4A UNIPROT A3EZI9 NS3 more at DrugCentral | EMA | |||
