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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TELAPREVIR DISCONTINUED
| TELAPREVIR | HEPATITIS C VIRUS (HCV) NS3/4A PROTEASE INHIBITOR | ORAL | Cmax 5.16 MICROMOLAR (750 MILLIGRAM) VD 252 LITER PPB 67 PERCENT Cl 32.4 LITER / HOUR HT 4.4 HOUR (750 MILLIGRAM) SOLUBILITY IN WATER OF 0.0047 MILLIGRAM / MILLILITER | NS3/4A PROTEASE | Hepatitis C virus serine protease, NS3,NS4A UNIPROT A3EZI9 NS3 more at DrugCentral | EMA | |||
