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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GABAPENTIN ENACARBIL (has an active metabolite)
| GABAPENTIN ENACARBIL | NERVOUS SYSTEM | ORAL | SOLUBILITY 0.5 MILLIGRAM / MILLILITER IN WATER | VOLTAGE-GATED CALCIUM CHANNEL (PMID26680202) | Voltage-dependent calcium channel subunit alpha-2,delta-1 UNIPROT P54289 CACNA2D1 -- Voltage-dependent calcium channel subunit alpha-2,delta-2 UNIPROT Q9NY47 CACNA2D2 more at DrugCentral | EMA | |||
