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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFTAROLINE (has an active metabolite)
| CEFTAROLINE | ANTIINFECTIVE | INTRAVENOUS | Cmax 27.7 MICROMOLAR (600 MILLIGRAM) VD 19.9 LITER (600 MILLIGRAM) PPB 20 PERCENT Cl 9.58 LITER / HOUR (600 MILLIGRAM) HT 1.6 HOUR (600 MILLIGRAM) SOLUBILITY WATER SOLUBLE PRODRUG OF CEFTAROLINE | PENICILLIN-BINDING PROTEIN 1B PENICILLIN-BINDING PROTEIN 1A PENICILLIN-BINDING PROTEIN 2A | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
